The difference between sensitivity, specificity and positive predictive value in NIPT, and why a high-risk result is often not what it appears.
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What non-invasive prenatal testing screens for, when it can be taken, how accurate it really is and why it is a screening test rather than a diagnosis.
How NIPT determines fetal sex, how accurate it is from 10 weeks, the recognised causes of discordant results, and the clinical reasons it matters.
What fetal fraction is, why a NIPT sample can return no result, what raises and lowers it, and why repeated failure is itself clinically meaningful.
A complete list of what NIPT screens for, how well it performs for each, and the important conditions it does not cover at all.
Why NIPT starts at 10 weeks, how gestational age affects fetal fraction, and how to plan timing around the dating scan and confirmatory options.
Why NIPT sometimes uncovers findings relating to the mother rather than the pregnancy, how often this happens, and what follow-up involves.